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Moldy Corn Poisoning or Leukoencephalomalacia in Horses

It has been long recognized that a toxin forms in poorly stored corn that causes a serious disease of the brain in horses, leukoencephalomalacia. The toxin fumonisin B1 has been identified as the cause. The toxin is produced by the fungus Fusarium moniliforme. Minute quantities of the toxin cause serious disease so frequently the feed appears normal. LEM has a history of coming in outbreaks when the weather has been wet.

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A disease of the white matter of the cerebral cortex resulting from the ingestion of corn or corn stalks which are contaminated with Fusarium moniliforme which produces the toxic compound. Mold may also contaminate pelleted rations which combine grain and roughage.

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